To wean or not to wean: A practical patient focused guide to ventilator weaning Review

  


Authors: Akella, P.; Voigt, L. P.; Chawla, S.
Review Title: To wean or not to wean: A practical patient focused guide to ventilator weaning
Abstract: Since the inception of critical care medicine and artificial ventilation, literature and research on weaning has transformed daily patient care in intensive care units (ICU). As our knowledge of mechanical ventilation (MV) improved, so did the need to study patient-ventilator interactions and weaning predictors. Randomized trials have evaluated the use of protocol-based weaning (vs. usual care) to study the duration of MV in ICUs, different techniques to conduct spontaneous breathing trials (SBT), and strategies to eventually extubate a patient whose initial SBT failed. Despite considerable milestones in the management of multiple diseases contributing to reversible respiratory failure, in the application of early rehabilitative interventions to preserve muscle integrity, and in ventilator technology that mitigates against ventilator injury and dyssynchrony, major barriers to successful liberation from MV persist. This review provides a broad encompassing view of weaning classification, causes of weaning failure, and evidence behind weaning predictors and weaning modes. © The Author(s) 2022.
Keywords: intensive care unit; intensive care units; respiratory insufficiency; artificial ventilation; respiratory failure; weaning; mechanical ventilation; procedures; respiration, artificial; humans; human; ventilators, mechanical; ventilator weaning; mechanical ventilator; spontaneous breathing trial; ventilator discontinuation
Journal Title: Journal of Intensive Care Medicine
Volume: 37
Issue: 11
ISSN: 0885-0666
Publisher: Sage Publications  
Date Published: 2022-11-01
Start Page: 1417
End Page: 1425
Language: English
DOI: 10.1177/08850666221095436
PUBMED: 35815895
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85133929931&doi=10.1177%2f08850666221095436&partnerID=40&md5=7866215245d3b6158bde141a26f06dfb
Notes: Review -- Export Date: 1 November 2022 -- Source: Scopus
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MSK Authors
  1. Sanjay Chawla
    49 Chawla
  2. Louis Pierre-Paul Voigt
    85 Voigt
  3. Padmastuti Akella
    5 Akella
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