The American College of Surgeons Surgical Risk Calculator performs well for pulmonary resection: A validation study Journal Article


Authors: Chudgar, N.; Yan, S.; Hsu, M.; Tan, K. S.; Gray, K. D.; Molena, D.; Jones, D. R.; Rusch, V. W.; Rocco, G.; Isbell, J. M.
Article Title: The American College of Surgeons Surgical Risk Calculator performs well for pulmonary resection: A validation study
Abstract: Objective: The American College of Surgeons National Surgical Quality Improvement Program Surgical Risk Calculator (NSQIP SRC) was developed to estimate the risk of postoperative morbidity and mortality within 30 days of an operation. We sought to externally evaluate the performance of the NSQIP SRC for patients undergoing pulmonary resection. Methods: Patients undergoing pulmonary resection at our center between January 2016 and December 2018 were included. Using data from our institution's prospectively maintained Society of Thoracic Surgeons General Thoracic Database, we identified 2514 patients. We entered requisite patient demographic information, preoperative risk factors, and procedural details into the online calculator. Predicted performance of the calculator versus observed outcomes was assessed by discrimination (concordance index [C-index]) and calibration. Results: The observed and predicted probabilities of any complication were 8.3% and 9.9%, respectively, and of serious complications were 7.4% and 9.2%, respectively. Observed and predicted 30-day mortality were 0.5% and 0.9%, respectively. The C-index for readmission was 0.644; the C-indices corresponding to all other outcomes in the NSQIP SRC ranged from 0.703 to 0.821. Calibration curves indicated excellent calibration for all binary end points, with the exception of renal failure (predicted underestimated observed probabilities), discharge to a nursing or rehabilitation facility (overestimated), and sepsis (overestimated). Correlation between predicted and observed length of stay was moderate (Spearman coefficient, 0.562), and calibration was good. Conclusions: Except for readmission, renal failure, discharge to a location other than home, and sepsis, the NSQIP SRC can be used to reasonably predict postoperative complications in patients undergoing pulmonary resection. © 2021 The American Association for Thoracic Surgery
Keywords: lung resection; nsqip; surgical risk calculator; surgical risk prediction
Journal Title: Journal of Thoracic and Cardiovascular Surgery
Volume: 163
Issue: 4
ISSN: 0022-5223
Publisher: Mosby Elsevier  
Date Published: 2022-04-01
Start Page: 1509
End Page: 1516.e1
Language: English
DOI: 10.1016/j.jtcvs.2021.01.036
PUBMED: 33610360
PROVIDER: scopus
PMCID: PMC8292429
DOI/URL:
Notes: Article -- Export Date: 1 April 2022 -- Funding details: National Institutes of Health, NIH -- Funding details: National Cancer Institute, NCI, P30CA008748 -- Funding text 1: This work was supported in part by National Institutes of Health/National Cancer Institute Cancer Center Support Grant P30CA008748; the sponsor played no role in any aspect of the work. -- Funding text 2: This work was supported in part by National Institutes of Health / National Cancer Institute Cancer Center Support Grant P30CA008748 ; the sponsor played no role in any aspect of the work. -- Source: Scopus
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MSK Authors
  1. Meier Hsu
    166 Hsu
  2. Valerie W Rusch
    827 Rusch
  3. David Randolph Jones
    367 Jones
  4. Daniela   Molena
    225 Molena
  5. Neel Pankaj Chudgar
    15 Chudgar
  6. Kay See   Tan
    211 Tan
  7. James Michael Isbell
    106 Isbell
  8. Gaetano Rocco
    91 Rocco
  9. Katherine D. Gray
    12 Gray
  10. Shi Yan
    8 Yan