External validation of surgical risk preoperative assessment system in pulmonary resection Journal Article


Authors: Chudgar, N. P.; Yan, S.; Hsu, M.; Tan, K. S.; Gray, K. D.; Nobel, T.; Molena, D.; Sihag, S.; Bott, M.; Jones, D. R.; Rusch, V. W.; Rocco, G.; Isbell, J. M.
Article Title: External validation of surgical risk preoperative assessment system in pulmonary resection
Abstract: Background: Accurate preoperative risk assessment is necessary for informed decision making for patients and surgeons. Several preoperative risk calculators are available but few have been examined in the general thoracic surgical patient population. The Surgical Risk Preoperative Assessment System (SURPAS), a risk-assessment tool applicable to a wide spectrum of surgical procedures, was developed to predict the risks of common adverse postoperative outcomes using a parsimonious set of preoperative input variables. We sought to externally validate the performance of SURPAS for postoperative complications in patients undergoing pulmonary resection. Methods: Between January 2016 and December 2018, 2514 patients underwent pulmonary resection at our center. Using data from our institution's prospectively maintained database, we calculated the predicted risks of 12 categories of postoperative outcomes using the latest version of SURPAS. Performance of SURPAS against observed patient outcomes was assessed by discrimination (concordance index) and calibration (calibration curves). Results: The discrimination ability of SURPAS was moderate across all outcomes (concordance indices, 0.640 to 0.788). Calibration curves indicated good calibration for all outcomes except infectious and cardiac complications, discharge to a location other than home, and mortality (all overestimated by SURPAS). Conclusions: SURPAS demonstrates outcomes for pulmonary resections with reasonable predictive ability. Discretion should be applied when assessing risk for postoperative infectious and cardiac complications, discharge to a location other than home, and mortality. Although the parsimonious nature of SURPAS is one of its strengths, its performance might be improved by including additional factors known to influence outcomes after pulmonary resection, such as sex and pulmonary function. © 2021 The Society of Thoracic Surgeons
Journal Title: Annals of Thoracic Surgery
Volume: 112
Issue: 1
ISSN: 0003-4975
Publisher: Elsevier Science, Inc.  
Date Published: 2021-07-01
Start Page: 228
End Page: 237
Language: English
DOI: 10.1016/j.athoracsur.2020.08.023
PUBMED: 33075325
PROVIDER: scopus
PMCID: PMC8100919
DOI/URL:
Notes: Conference Paper -- Export Date: 2 August 2021 -- Source: Scopus
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MSK Authors
  1. Meier Hsu
    169 Hsu
  2. Valerie W Rusch
    864 Rusch
  3. Matthew Bott
    135 Bott
  4. David Randolph Jones
    417 Jones
  5. Daniela   Molena
    270 Molena
  6. Neel Pankaj Chudgar
    15 Chudgar
  7. Kay See   Tan
    241 Tan
  8. James Michael Isbell
    127 Isbell
  9. Smita Sihag
    96 Sihag
  10. Tamar B Nobel
    41 Nobel
  11. Gaetano Rocco
    130 Rocco
  12. Katherine D. Gray
    24 Gray
  13. Shi Yan
    8 Yan