Thyroid Carcinoma, version 2.2022, NCCN Clinical Practice Guidelines in Oncology Guidelines


Authors: Haddad, R. I.; Bischoff, L.; Ball, D.; Bernet, V.; Blomain, E.; Busaidy, N. L.; Campbell, M.; Dickson, P.; Duh, Q. Y.; Ehya, H.; Goldner, W. S.; Guo, T.; Haymart, M.; Holt, S.; Hunt, J. P.; Iagaru, A.; Kandeel, F.; Lamonica, D. M.; Mandel, S.; Markovina, S.; McIver, B.; Raeburn, C. D.; Rezaee, R.; Ridge, J. A.; Roth, M. Y.; Scheri, R. P.; Shah, J. P.; Sipos, J. A.; Sippel, R.; Sturgeon, C.; Wang, T. N.; Wirth, L. J.; Wong, R. J.; Yeh, M.; Cassara, C. J.; Darlow, S.
Title: Thyroid Carcinoma, version 2.2022, NCCN Clinical Practice Guidelines in Oncology
Abstract: Differentiated thyroid carcinomas is associated with an excellent prognosis. The treatment of choice for differentiated thyroid carcinoma is surgery, followed by radioactive iodine ablation (iodine-131) in select patients and thyroxine therapy in most patients. Surgery is also the main treatment for medullary thyroid carcinoma, and kinase inhibitors may be appropriate for select patients with recurrent or persistent disease that is not resectable. Anaplastic thyroid carcinoma is almost uniformly lethal, and iodine-131 imaging and radioactive iodine cannot be used. When systemic therapy is indicated, targeted therapy options are preferred. This article describes NCCN recommendations regarding management of medullary thyroid carcinoma and anaplastic thyroid carcinoma, and surgical management of differentiated thyroid carcinoma (papillary, follicular, Hürthle cell carcinoma).
Keywords: adenocarcinoma; pathology; radioactive iodine; iodine radioisotopes; carcinoma; thyroid carcinoma; thyroid neoplasms; thyroid tumor; carcinoma, neuroendocrine; iodine; humans; human; thyroid carcinoma, anaplastic
Journal Title: Journal of the National Comprehensive Cancer Network
Volume: 20
Issue: 8
ISSN: 1540-1405
Publisher: Harborside Press  
Date Published: 2022-08-01
Start Page: 925
End Page: 951
Language: English
DOI: 10.6004/jnccn.2022.0040
PUBMED: 35948029
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 1 September 2022 -- Source: Scopus
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  1. Richard J Wong
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  2. Jatin P Shah
    721 Shah