Cancer and cancer treatment-related cognitive impairment Book Section
| Authors: | Root, J. C.; Ryan, E.; Ahles, T. A. |
| Editors: | Alosco, M. L.; Stern, R. A. |
| Article/Chapter Title: | Cancer and cancer treatment-related cognitive impairment |
| Abstract: | As the population of cancer survivors has grown into the millions, there is increasing emphasis on understanding how late effects of treatment impact survivors' ability return to work/school, ability to function and live independently, and overall quality of life. Cognitive changes are one of the most feared problems among cancer survivors. This chapter describes the growing literature examining cognitive changes associated with non-central nervous system cancer and cancer treatment. Typical elements of cancer treatment are discussed, followed by a description of clinical presentation, self-reported and objectively assessed cognitive findings, and results of structural and functional neuroimaging research. Genetic and other risk factors for cognitive decline following treatment are identified and discussed, together with biomarkers and animal models of treatment-related effects. This Is followed by a discussion of behavioral and pharmacologic treatments. Finally, challenges and recommendations for future research are provided to help guide subsequent research and theoretical models. (PsycInfo Database Record (c) 2021 APA, all rights reserved) |
| Keywords: | genetics; chemotherapy; neuroimaging; biomarkers; risk factors; cognition; radiation therapy; aging; endocrine therapy; cancer treatment; cognitive impairment; cancer; cognitive decline; cognitive changes; non-central nervous system cancer |
| Book Title: | The Oxford Handbook of Adult Cognitive Disorders |
| ISBN: | 9780190664121 |
| Publisher: | Oxford University Press |
| Publication Place: | New York, NY |
| Date Published: | 2019-01-01 |
| Start Page: | 61 |
| End Page: | 83 |
| Language: | English |
| ACCESSION: | 2019-26827-004 |
| PROVIDER: | Ovid Technologies |
| PROVIDER: | psycinfo |
| DOI: | 10.1093/oxfordhb/9780190664121.013.4 |
| DOI/URL: | |
| Notes: | Book Chapter: 4 -- Source: APA PsycInfo |
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