Abstract: |
(from the chapter) Increasing research has focused on cognitive changes associated with cancer and cancer treatments. Patients with cancer of the central nervous system (CNS) often experience cognitive dysfunction as a result of the tumor and its treatment, including surgery, radiotherapy (RT), and chemotherapy.' As effective treatment interventions have increased survival, the relevance of including cognitive evaluations as outcome variables in neuro-oncology research has been recognized, and the National Cancer Institute (NCI) Brain Tumor Progress Review Group Report has recommended that routine cognitive assessment become the standard care for patients with brain tumors. Guidelines for the neuropsychological assessment of patients with brain tumors within the context of clinical trials have been developed,' and there has been an increase in the number of studies demonstrating the feasibility and relevance of studying cognitive functions in this population. A growing body of evidence has documented declines in cognitive abilities in individuals diagnosed with and treated for non-CNS cancer, including breast and prostate cancer, although the bulk of the research has been done with breast cancer patients and survivors. The goals of this chapter are to review the phenomenon of cancer-related cognitive dysfunction and to present a model for a multifactorial etiology, common assessment tools, and currently used methods of treatment and management. (PsycINFO Database Record (c) 2015 APA, all rights reserved). |