Intraperitoneal chemotherapy: Technical experience at five institutions Journal Article
| Authors: | Piccart, M. J.; Speyer, J. L.; Markman, M.; ten Bokkel Huinink, W.; Alberts, D.; Jenkins, J.; Muggia, F. |
| Article Title: | Intraperitoneal chemotherapy: Technical experience at five institutions |
| Abstract: | With the rapid expansion of research programs examining intraperitoneal chemotherapy for ovarian cancer and other intraabdominal malignancies, there is a need for a reliable and safe access to the peritoneal cavity. The technical experience accumulated with either the Tenckhoff catheter or the Port-A-Cath in 288 patients treated at five institutions showed a low incidence of catheter-related peritonitis (5% and 8%, respectively), skin infection (6.6% and 0%), and bowel perforation following surgical implantation (3.5% and 1.3%). Postoperative leakage of intraabdominal fluid, bleeding, or ileus were uncommon and easily controlled. Drainage failure was the major problem with both systems; occurring in 45% of patients. Although both systems are workable, improved catheters for the administration of intraperitoneal chemotherapy are warranted. © 1985. |
| Keywords: | cancer chemotherapy; clinical article; antineoplastic agents; antineoplastic agent; metastasis; catheterization; therapy; infusions, parenteral; catheters, indwelling; female genital system; catheter; complication; peritoneum; peritoneal cavity; digestive system; intraperitoneal drug administration; humans; human |
| Journal Title: | Seminars in Oncology |
| Volume: | 12 |
| Issue: | 3 Suppl. 4 |
| ISSN: | 0093-7754 |
| Publisher: | Elsevier Inc. |
| Date Published: | 1985-09-01 |
| Start Page: | 90 |
| End Page: | 96 |
| Language: | English |
| PUBMED: | 4048981 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 26 October 2021 -- Source: Scopus |
