Treatment of severe coagulopathy in the Kasabach-Merritt syndrome with aminocaproic acid and cryoprecipitate Journal Article
| Authors: | Warrell, R. P. Jr; Kempin, S. J. |
| Article Title: | Treatment of severe coagulopathy in the Kasabach-Merritt syndrome with aminocaproic acid and cryoprecipitate |
| Abstract: | The Kasabach-Merritt syndrome is characterized by thrombocytopenia associated with solitary or multiple hemangiomas.1 Coagulation studies in patients with this disease frequently reveal a profile similar to that of disseminated intravascular coagulation.23 The disorder is of particular clinical interest since complete eradication of the tumor by surgical excision or radiation eliminates the coagulopathy.45 Although the syndrome is primarily a disease of infancy, some patients survive for long periods, particularly if the coagulation defect is mild. In the absence of treatment, fatal hemorrhage can result.456 The syndrome is unique in that the coagulopathy is believed to be a manifestation of clotting and. © 1985, Massachusetts Medical Society. All rights reserved. |
| Keywords: | unclassified drug; case report; thrombocytopenia; thrombosis; cardiovascular system; heparin; radioisotope; drug therapy; blood clotting disorder; therapy; hemangioma; intravenous drug administration; oral drug administration; cryoprecipitate; aminocaproic acid; human; priority journal; article; kasabach merritt syndrome; blood and hemopoietic system; peripheral vascular system; nafazatrom; fibrinogen i 125 |
| Journal Title: | New England Journal of Medicine |
| Volume: | 313 |
| Issue: | 5 |
| ISSN: | 0028-4793 |
| Publisher: | Massachusetts Medical Society |
| Date Published: | 1985-08-01 |
| Start Page: | 309 |
| End Page: | 312 |
| Language: | English |
| DOI: | 10.1056/nejm198508013130507 |
| PROVIDER: | scopus |
| PUBMED: | 3925341 |
| DOI/URL: | |
| Notes: | Article -- Export Date: 26 October 2021 -- Source: Scopus |
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