Acute promyelocytic leukemia: A rare presentation without systemic disease Journal Article


Authors: Ladak, N.; Liu, Y.; Burke, A.; Lin, O.; Chan, A.
Article Title: Acute promyelocytic leukemia: A rare presentation without systemic disease
Abstract: Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia characterized by an abnormal proliferation of promyelocytes. It is often associated with an aggressive clinical presentation involving complex coagulopathies including disseminated intravascular coagulation, with a significant risk of bleeding and/or thrombosis if treatment with all-trans-retinoic acid (ATRA) is not rapidly initiated. Here we present a unique case of APL which was isolated to femoral bone lesions, without definitive evidence of peripheral blood or bone marrow involvement, and without systemic sequelae. © 2024 The Authors
Keywords: acute leukemia; bone; acute promyelocytic leukemia; acute myeloid leukemia; apl
Journal Title: Human Pathology Reports
Volume: 37
ISSN: 2772-736X
Publisher: Elsevier Inc.  
Date Published: 2024-09-01
Start Page: 300753
Language: English
DOI: 10.1016/j.hpr.2024.300753
PROVIDER: scopus
PMCID: PMC11440618
PUBMED: 39351214
DOI/URL:
Notes: Article -- MSK Cancer Center Support Grant (P30 CA008748) acknowledged in PDF -- MSK corresponding author is Alexander Chan -- Source: Scopus
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
  1. Oscar Lin
    307 Lin
  2. Alexander Yoshifumi Chan
    42 Chan
  3. Ying Liu
    33 Liu
  4. Amanda Phyllis Burke
    1 Burke
  5. Nurfiza Ladak
    2 Ladak