Authors: | Ladak, N.; Liu, Y.; Burke, A.; Lin, O.; Chan, A. |
Article Title: | Acute promyelocytic leukemia: A rare presentation without systemic disease |
Abstract: | Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia characterized by an abnormal proliferation of promyelocytes. It is often associated with an aggressive clinical presentation involving complex coagulopathies including disseminated intravascular coagulation, with a significant risk of bleeding and/or thrombosis if treatment with all-trans-retinoic acid (ATRA) is not rapidly initiated. Here we present a unique case of APL which was isolated to femoral bone lesions, without definitive evidence of peripheral blood or bone marrow involvement, and without systemic sequelae. © 2024 The Authors |
Keywords: | acute leukemia; bone; acute promyelocytic leukemia; acute myeloid leukemia; apl |
Journal Title: | Human Pathology Reports |
Volume: | 37 |
ISSN: | 2772-736X |
Publisher: | Elsevier Inc. |
Date Published: | 2024-09-01 |
Start Page: | 300753 |
Language: | English |
DOI: | 10.1016/j.hpr.2024.300753 |
PROVIDER: | scopus |
PMCID: | PMC11440618 |
PUBMED: | 39351214 |
DOI/URL: | |
Notes: | Article -- MSK Cancer Center Support Grant (P30 CA008748) acknowledged in PDF -- MSK corresponding author is Alexander Chan -- Source: Scopus |