The response of fibronectin to differing parenteral caloric sources in normal man Journal Article


Authors: Horowitz, G. D.; Groeger, J. S.; Legaspi, A.; Lowry, S. F.
Article Title: The response of fibronectin to differing parenteral caloric sources in normal man
Abstract: The relationship between circulating fibronectin concentration and nutritional status was examined in eight healthy male (31 ± 1 yr old) volunteers in three nutritional states: the postabsorptive state, after 10 days of protein-caloric starvation, and during the 10th day of refeeding by total parenteral nutrition. Plasma fibronectin was significantly decreased from 330 ± 22 to 154 ± 11 μg/ml (p < 0.001) from the postabsorptive to starved state which was accompanied by appropriate changes in body weight, anthropometric measurements, and nitrogen balance. Plasma fibronectin levels were restored to 402 ± 39 μg/ml following 10 days of total parenteral nutrition. The plasma fibronectin response was greater (p < 0.05) during total parenteral nutrition with dextrose as the nonprotein calorie source as compared to a 50% dextrose/50% lipid regimen. These results suggest that the calorie source must be considered during interpretation of plasma fibronectin levels in patients undergoing parenteral nutrition. (Journal of Parenteral and Enteral Nutrition 9:435-438, 1985). © 1985, Sage Publications. All rights reserved.
Keywords: adult; human cell; nutritional status; total parenteral nutrition; glucose; lipids; nitrogen; muscles; fibronectin; parenteral nutrition; skinfold thickness; fibronectins; human; male; priority journal; support, non-u.s. gov't; support, u.s. gov't, p.h.s.; blood and hemopoietic system; protein-energy malnutrition
Journal Title: Journal of Parenteral and Enteral Nutrition
Volume: 9
Issue: 4
ISSN: 0148-6071
Publisher: Sage Publications  
Date Published: 1985-07-01
Start Page: 435
End Page: 438
Language: English
DOI: 10.1177/0148607185009004435
PROVIDER: scopus
PUBMED: 3928916
DOI/URL:
Notes: Article -- Export Date: 26 October 2021 -- Source: Scopus
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