Lymphokine-activated killer cells are generated before classical cytotoxic T lymphocytes after bone marrow transplantation in mice Journal Article


Authors: Merluzzi, V. J.; Savage, D. M.; Smith, M. D.; Last-Barney, K.; Mertelsmann, R.; Moore, M. A.; Welte, K.
Article Title: Lymphokine-activated killer cells are generated before classical cytotoxic T lymphocytes after bone marrow transplantation in mice
Abstract: Lymphokine-activated killer (LAK) cells are demonstrable within 2 wk after syngeneic or allogeneic (H-2-compatible) bone marrow transplantation in mice. Classical cytotoxic T lymphocytes (CTL) are not active until at least 4 wk after transplant. Both LAK cells and CTL bear the Thy-1 marker and do not possess the murine natural killer cell marker asialo GM1.
Keywords: nonhuman; mouse; animals; mice; interleukin 2; animal experiment; in vitro study; time factors; mice, inbred strains; cytotoxic t lymphocyte; t-lymphocytes, cytotoxic; killer cells, natural; cytotoxicity, immunologic; bone marrow transplantation; interleukin-2; antigens, surface; killer cell; male; female; priority journal; killer cells; blood and hemopoietic system
Journal Title: Journal of Immunology
Volume: 135
Issue: 3
ISSN: 0022-1767
Publisher: The American Association of Immunologists, Inc  
Date Published: 1985-09-01
Start Page: 1702
End Page: 1706
Language: English
PROVIDER: scopus
PUBMED: 3894518
DOI/URL:
Notes: Article -- Export Date: 26 October 2021 -- Source: Scopus
Citation Impact
MSK Authors
  1. Malcolm A S Moore
    549 Moore
  2. Karl Welte
    77 Welte