Therapeutic strategies for systemic therapies of human papillomavirus-related oropharyngeal cancer Review

   


Authors: Hung, T. K. W.; Ho, A. L.; Pfister, D. G.
Review Title: Therapeutic strategies for systemic therapies of human papillomavirus-related oropharyngeal cancer
Abstract: Our understanding of human papillomavirus (HPV)-related oropharyngeal cancer (OPC) and its molecular basis continues to evolve and produce important insights into customized therapeutic strategies. Novel therapeutics exploiting HPV-related targets are being evaluated in the incurable setting, while the favorable prognosis of locoregionally advanced disease has stimulated investigation into de-escalation strategies. There is much opportunity for better personalization of standard therapy according to HPV status. This review discusses both current and investigational therapeutic strategies for HPV-related OPC. © 2021 Wiley Periodicals LLC
Keywords: chemotherapy; immunotherapy; targeted therapy; oropharyngeal cancer; human papilloma virus
Journal Title: Journal of Surgical Oncology
Volume: 124
Issue: 6
ISSN: 0022-4790
Publisher: Wiley Blackwell  
Date Published: 2021-11-01
Start Page: 952
End Page: 961
Language: English
DOI: 10.1002/jso.26688
PROVIDER: scopus
PMCID: PMC8500927
PUBMED: 34585389
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115844484&doi=10.1002%2fjso.26688&partnerID=40&md5=9e6b6b0cea23d39657fb03f523487d41
Notes: Review --Source: Scopus
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MSK Authors
  1. David G Pfister
    389 Pfister
  2. Alan Loh Ho
    237 Ho
  3. Tony K.W. Hung
    32 Hung
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