Therapeutic strategies: Surgery for human papillomavirus-associated oropharyngeal carcinoma Review

  


Authors: Mclean, T.; Fitzgerald, C.; Boyle, J. O.
Review Title: Therapeutic strategies: Surgery for human papillomavirus-associated oropharyngeal carcinoma
Abstract: Treatment of oropharyngeal cancer (OPC) has undergone considerable evolution since the discovery of human papillomavirus (HPV)-associated OPC. It is widely understood that HPV OPC affects a younger population and standard treatment offers improved oncologic outcomes compared with non-HPV OPC but can cause significant toxicities and long-term side effects. Surgery for treatment de-escalation is an active area of research. The purpose of this review is to explore surgery as it relates to the treatment of HPV OPC with a focus on the evolution of treatment, rationale for surgery, surgical techniques, outcomes, and the role of surgery in de-escalation of treatment. © 2021 Wiley Periodicals LLC
Keywords: surgery; oropharynx; hpv; tos; deintensification
Journal Title: Journal of Surgical Oncology
Volume: 124
Issue: 6
ISSN: 0022-4790
Publisher: Wiley Blackwell  
Date Published: 2021-11-01
Start Page: 935
End Page: 944
Language: English
DOI: 10.1002/jso.26695
PROVIDER: scopus
PUBMED: 34595753
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85116812393&doi=10.1002%2fjso.26695&partnerID=40&md5=080e53e2c21e31acb52d32f2c9c18f55
Notes: Review -- Source: Scopus
Altmetric
What is Altmetric?
Citation Impact
What is Dimensions Citation Badge?
BMJ Impact Analytics
MSK Authors
  1. Jay O Boyle
    148 Boyle
  2. Conall Fitzgerald
    27 Fitzgerald
  3. Andrew Timothy Mclean
    9 Mclean
Related MSK Work