Synthesis of furo[3,2-d]pyrimidine nucleosides: A novel c-nucleoside isostere of adenosine Journal Article
| Authors: | Bhattacharya, B. K.; Lim, M. I.; Otter, B. A.; Klein, R. S. |
| Article Title: | Synthesis of furo[3,2-d]pyrimidine nucleosides: A novel c-nucleoside isostere of adenosine |
| Abstract: | The synthesis of 4-amino-7-(β- D-ribofuranosyl)-furo[3,2-d]pyrimidine, a new C-nucleoside analogof adenosine, is described. It involves base-catalyzed cyclization of the 2-(ribofuranosyl)-2-cyano ethers 3 to afford the ribosyl-3-amino-2-cyanofurans 4a and 4β, followed by a two step conversion into the desired furo[3,2-d]pyrimidine system. © 1986. |
| Journal Title: | Tetrahedron Letters |
| Volume: | 27 |
| Issue: | 7 |
| ISSN: | 0040-4039 |
| Publisher: | Pergamon-Elsevier Science Ltd |
| Date Published: | 1986-01-01 |
| Start Page: | 815 |
| End Page: | 818 |
| Language: | English |
| DOI: | 10.1016/s0040-4039(00)84108-8 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 18 August 2021 -- Source: Scopus |
