Metastatic neuroblastoma after 52 years of apparent dormancy - To the editor Journal Article


Authors: Kushner, B. H.; Helson, L.; Lane, J. M.; Hajdu, S. I.
Article Title: Metastatic neuroblastoma after 52 years of apparent dormancy - To the editor
Abstract: To the Editor: We wish to report a case in which an 81-year-old man had a disseminated neuroblastoma that apparently arose from a posterior mediastinal tumor that had been present for at least 52 years. This case may offer insight into the pathogenesis of neuroblastoma. In 1933, when he was 29, the patient presented with pain on the left side of the chest. Radiography at that time and in subsequent decades revealed a large posterior mediastinal mass; no specific therapy was offered. Angiography and computerized tomography (CT) in 1978 defined the mass as a partly calcified, paraspinal tumor (3.5 by. © 1986, Massachusetts Medical Society. All rights reserved.
Keywords: aged; case report; histology; time factors; neuroblastoma; diagnosis; mediastinal neoplasms; nervous system; dormancy; autonomic nervous system; human; male; priority journal
Journal Title: New England Journal of Medicine
Volume: 315
Issue: 3
ISSN: 0028-4793
Publisher: Massachusetts Medical Society  
Date Published: 1986-07-17
Start Page: 196
End Page: 197
Language: English
DOI: 10.1056/nejm198607173150318
PUBMED: 3724812
PROVIDER: scopus
DOI/URL:
Notes: Letter -- Export Date: 18 August 2021 -- Source: Scopus
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  1. Brian Kushner
    312 Kushner
  2. Joseph M. Lane
    66 Lane
  3. Steven I. Hajdu
    80 Hajdu
  4. Lawrence Helson
    26 Helson