Hypertrophic olivary degeneration resulting from posterior fossa masses and their treatments Journal Article


Authors: Hirano, M.; Hatzoglou, V.; Karimi, S.; Young, R. J.
Article Title: Hypertrophic olivary degeneration resulting from posterior fossa masses and their treatments
Abstract: Purpose: Characterize hypertrophic olivary degeneration (HOD) that develops from posterior fossa masses and their treatments. Methods: Retrospectively reviewed MR images and clinical data of 10 patients with posterior fossa masses and HOD. Results: Eight patients had cerebellar lesions, and two patients had pontine lesions. Lesions consisted of tumors, demyelination, and nonspecific necrosis. MRI showed T2 hyperintense signal in the inferior olive a median 86 days after the diagnosis of a posterior fossa lesion. HOD presented prior to surgery (n=2), after surgery (n=3), after surgery/radiation therapy (n=4), or without treatment (n=1). Conclusions: HOD may develop from posterior fossa masses and surgical and/or radiation therapy. © 2015.
Keywords: adult; child; clinical article; preschool child; aged; middle aged; cancer surgery; disease course; cancer radiotherapy; gadolinium; neuroimaging; magnetic resonance imaging; tumor localization; radiotherapy; medical record review; necrosis; tumors; contrast enhancement; glioblastoma; diagnosis; medulloblastoma; brain disease; surgery; disease duration; neuroectoderm tumor; hemangioblastoma; mri; mr images; posterior cranial fossa tumor; steroid therapy; diffusion tensor imaging; pilocytic astrocytoma; demyelinating disease; clinical data; glioneuronal tumor; nervous system tumor; surgical therapy; hypertrophic olivary degeneration; time to treatment; human; male; female; priority journal; article; all oncology; radiation-therapy tumor; surgical-therapy tumor; histiocytic inflammation; metastatic renal cortical carcinoma
Journal Title: Clinical Imaging
Volume: 39
Issue: 5
ISSN: 0899-7071
Publisher: Elsevier Inc.  
Date Published: 2015-09-01
Start Page: 787
End Page: 790
Language: English
DOI: 10.1016/j.clinimag.2015.05.015
PROVIDER: scopus
PUBMED: 26104225
PMCID: PMC4753058
DOI/URL:
Notes: Export Date: 2 October 2015 -- Source: Scopus
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  1. Robert J Young
    228 Young
  2. Sasan Karimi
    114 Karimi
  3. Miki   Hirano
    2 Hirano