Biotransformation of benzo(a)pyrene by Mercenaria mercenaria and Crassostrea virginica Conference Paper
| Authors: | Anderson, R. S.; Angel, M. A. |
| Editors: | Poston, T. M.; Purdy, R. |
| Title: | Biotransformation of benzo(a)pyrene by Mercenaria mercenaria and Crassostrea virginica |
| Conference Title: | 9th Symposium on Aquatic Toxicology |
| Abstract: | Using a sensitive, radioisotopic assay for aryl hydrocarbon hydroxylase (AHH), a comparatively low level of benzo(a)pyrene (BaP) metabolism was routinely measured in digestive gland homogenates. Attempts to induce overall BaP metabolism by exposure to Aroclor 1254, an inducer of mammalian AHH, were largely unsuccessful. However, Aroclor treatment produced an altered BaP metabolite profile for each bivalve species tested. The data suggest that BaP biotransformation by bivalve enzyme systems can yield both potentially carcinogenic (BaP 7,8-diol) and detoxified metabolites. However, no apparent activation of BaP by molluscan enzymes was seen using the Ames Salmonella tester strains. |
| Keywords: | metabolism; enzymes; biotransformation; hydrocarbons; water pollution - control; aquatic toxicology; environmental carcinogenesis |
| Journal Title | Aquatic Toxicology and Environmental Fate, 9th volume |
| Volume: | ASTM STP 921 |
| Conference Dates: | 1985 Oct 14-16 |
| Conference Location: | Philadelphia, PA |
| ISBN: | 978-0-8031-0489-1 |
| Publisher: | ASTM |
| Date Published: | 1986-12-01 |
| Start Page: | 241 |
| End Page: | 251 |
| Language: | English |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Conference Paper -- Export Date: 18 August 2021 -- Source: Scopus |
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