Low-grade myxofibrosarcoma: CT and MRI patterns in recurrent disease Journal Article


Authors: Waters, B.; Panicek, D. M.; Lefkowitz, R. A.; Antonescu, C. R.; Healey, J. H.; Athanasian, E. A.; Brennan, M. F.
Article Title: Low-grade myxofibrosarcoma: CT and MRI patterns in recurrent disease
Abstract: OBJECTIVE: Low-grade myxofibrosarcoma often relentlessly recurs after surgical resection, with an unusual infiltrative growth pattern and sometimes without a discrete tumor nodule at pathologic examination. This study was undertaken to determine and show patterns of recurrent low-grade myxofibrosarcoma at CT and MRI. CONCLUSION: Unlike in most other histologic types of low-grade soft-tissue sarcoma, recurrent low-grade myxofibrosarcoma often is infiltrative; shows a tapering, tail-like margin and superficial spreading configuration; and metastasizes to various distant sites, including lungs, pleura, bone, adrenal gland, soft tissue, and mesentery. Knowledge of these unusual characteristics is important in assessing the presence and extent of recurrent low-grade myxofibrosarcoma before surgical reexcision.
Keywords: adult; aged; middle aged; retrospective studies; nuclear magnetic resonance imaging; methodology; magnetic resonance imaging; computer assisted tomography; neoplasm recurrence, local; tomography, x-ray computed; retrospective study; fibrosarcoma; image enhancement; tumor recurrence; soft tissue neoplasms; soft tissue tumor
Journal Title: American Journal of Roentgenology
Volume: 188
Issue: 2
ISSN: 0361-803X
Publisher: American Roentgen Ray Society  
Date Published: 2007-02-01
Start Page: W193
End Page: 198
Language: English
DOI: 10.2214/ajr.05.1130
PUBMED: 17242227
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 5" - "Export Date: 17 November 2011" - "Source: Scopus"
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  1. Brendan Lawrence Waters
    1 Waters
  2. Murray F Brennan
    1059 Brennan
  3. David M Panicek
    134 Panicek
  4. Cristina R Antonescu
    895 Antonescu
  5. John H Healey
    547 Healey