Myxoinflammatory fibroblastic sarcoma: Clinical, imaging, management and outcome in 29 patients Journal Article


Authors: Kumar, R.; Lefkowitz, R. A.; Neto, A. D. R. T.
Article Title: Myxoinflammatory fibroblastic sarcoma: Clinical, imaging, management and outcome in 29 patients
Abstract: Objective: This retrospective study was undertaken to highlight clinical and magnetic resonance imaging features of myxoinflammatory fibroblastic sarcoma. Methods: The clinical records of 29 patients (14 men and 15 women) were analyzed. Results: The soft tissue tumors involved hand, wrist, foot and ankle in 21 patients, more proximal extremities in 7 patients, and neck in 1 patient. The tumors were subcutaneous in 11 patients, and intramuscular in 15 patients. On magnetic resonance imaging, these tumors had nonspecific features suggestive of benign and malignant lesions. An unusual tumor in hand indicated infection, whereas an intraarticular knee tumor mimicked pigmented villonodular synovitis. All tumors were surgically resected. Conclusions: Myxoinflammatory fibroblastic sarcoma, a rare low-grade subcutaneous soft tissue tumor of distal extremities with high local recurrence after resection can mimic several benign and malignant lesions on histopathology and imaging. Rarely, it can arise in muscles and tendons, occur in nonacral sites, be aggressive, and even metastasize. In most cases, surgical resection with wide margins can be curative with low local recurrence. © 2016 Wolters Kluwer Health, Inc. All rights reserved.
Keywords: infection; soft tissue sarcoma; myxoinflammatory fibroblastic sarcoma; pigmented villonodular synovitis; acral myxoinflammatory fibroblastic sarcoma
Journal Title: Journal of Computer Assisted Tomography
Volume: 41
Issue: 1
ISSN: 0363-8715
Publisher: Lippincott Williams & Wilkins  
Date Published: 2017-01-01
Start Page: 104
End Page: 115
Language: English
DOI: 10.1097/rct.0000000000000490
PROVIDER: scopus
PUBMED: 27560024
DOI/URL:
Notes: Article -- Export Date: 2 February 2017 -- Source: Scopus
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