Soft tissue sarcomas Journal Article


Authors: Lewis, J. J.; Brennan, M. F.
Article Title: Soft tissue sarcomas
Abstract: Soft tissue sarcomas are relatively rare tumors with an annual incidence of 5000 to 6000 in the United States. The primary therapy is surgical resection with an adequate margin of normal tissue. For patients at high risk local control is improved with postoperative adjuvant radiation. Local recurrence rates vary depending on the anatomic site. In extremity lesions one third of patients will have locally recurrent disease with a median disease-free interval of 18 months. Treatment results for extremity local recurrence may approach those for primary disease. Isolated pulmonary métastases may be resected with 20% to 30% 3-year survival rates. Patients with sarcomas in other sites present similar but more difficult problems in terms of local control and management of disseminated disease. Patients with unresectable pulmonary métastases or extrapulmonary metastatic sarcoma have a uniformly poor prognosis and are best treated with systemic chemotherapy.
Keywords: review; cancer staging; neoplasm staging; metastasis; pathology; sarcoma; neoplasm metastasis; soft tissue neoplasms; soft tissue tumor; humans; prognosis; human; male; female
Journal Title: Current Problems in Surgery
Volume: 33
Issue: 10
ISSN: 0011-3840
Publisher: Mosby Elsevier  
Date Published: 1996-10-01
Start Page: 821
End Page: 872
Language: English
PUBMED: 8885853
PROVIDER: scopus
DOI: 10.1016/S0011-3840(96)80013-X
DOI/URL:
Notes: Article -- Export Date: 22 November 2017 -- Source: Scopus
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  1. Murray F Brennan
    1059 Brennan
  2. Jonathan J Lewis
    109 Lewis