Authors: | Campbell, C.; Rudensky, A. Y. |
Title: | Immunotherapy breaches low-sugar dieting of tumor Treg cells |
Abstract: | Glycolysis supports effector T cell function but is detrimental to the immunosuppressive activity of regulatory T cells. In a recent issue of Nature, two papers address a role for glucose and lactate availability within the tumor microenvironment for the balance of pro- and anti-tumoral effects of T cells and the efficacy of neoadjuvant cancer immunotherapy. © 2021 Elsevier Inc. |
Journal Title: | Cell Metabolism |
Volume: | 33 |
Issue: | 5 |
ISSN: | 1550-4131 |
Publisher: | Elsevier Inc. |
Date Published: | 2021-05-04 |
Start Page: | 851 |
End Page: | 852 |
Language: | English |
DOI: | 10.1016/j.cmet.2021.04.010 |
PUBMED: | 33951469 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | Article -- Export Date: 1 June 2021 -- Source: Scopus |