COVID-19 in pediatric survivors of childhood cancer and hematopoietic cell transplantation from a single center in New York City Journal Article
| Authors: | Jimenez‐Kurlander, L.; Antal, Z.; DeRosa, A.; Diotallevi, D.; Pottenger, E.; Wilson, N.; Corcoran, S.; Boulad, F.; Friedman, D. N. |
| Article Title: | COVID-19 in pediatric survivors of childhood cancer and hematopoietic cell transplantation from a single center in New York City |
| Abstract: | Childhood cancer survivors are at increased risk for treatment-related late effects; data are lacking on how coronavirus disease 2019 (COVID-19) infection impacts this cohort. We assessed COVID-19-related symptoms, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) IgG seroprevalence, and rate of COVID-19-related hospitalization among 321 asymptomatic survivors of childhood cancer or transplantation seen for routine long-term follow-up between May and September 2020 in a New York City tertiary cancer center. While 10.9% (n = 35) reported possible COVID-19-related symptoms, 7.8% (n = 20) of those tested had positive SARS-CoV-2 IgG, and one patient (0.3%) required COVID-19-related hospitalization. This report suggests that childhood cancer survivors appear to be at relatively low risk for COVID-19 complications. © 2020 Wiley Periodicals LLC |
| Keywords: | adolescent; adult; child; major clinical study; allogeneic stem cell transplantation; doxorubicin; cancer combination chemotherapy; cancer patient; follow up; cohort analysis; obesity; melphalan; hematopoietic stem cell transplantation; retrospective study; thiotepa; childhood cancer; survivors; fever; myelodysplastic syndrome; immunoglobulin g; infant; neuroblastoma; newborn; lymphoma; comorbidity; headache; new york; childhood leukemia; non insulin dependent diabetes mellitus; clofarabine; respiratory failure; sleep disordered breathing; pandemic; childhood cancer survivor; acute myeloid leukemia; seroconversion; myocarditis; child hospitalization; seroprevalence; heart left ventricle hypertrophy; asymptomatic disease; human; male; female; priority journal; article; matched unrelated donor; severe acute respiratory syndrome coronavirus 2; coronavirus disease 2019; covid-19; sars-cov-2; asymptomatic carrier |
| Journal Title: | Pediatric Blood and Cancer |
| Volume: | 68 |
| Issue: | 3 |
| ISSN: | 1545-5009 |
| Publisher: | Wiley Periodicals, Inc |
| Date Published: | 2021-03-01 |
| Start Page: | e28857 |
| Language: | English |
| DOI: | 10.1002/pbc.28857 |
| PUBMED: | 33355979 |
| PROVIDER: | scopus |
| PMCID: | PMC7883208 |
| DOI/URL: | |
| Notes: | Article -- Export Date: 1 March 2021 -- Source: Scopus |
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