Morphological development of the mouse gonad in tda-1 XY sex reversal Journal Article
| Authors: | Nagamine, C. M.; Taketo, T.; Koo, G. C. |
| Article Title: | Morphological development of the mouse gonad in tda-1 XY sex reversal |
| Abstract: | tda-1 XY sex reversal occurs when the Y chromosome of at least some populations of wild Mus musculus domesticus is placed on the C57BL/6J genomic background. Gross anatomical observations have previously revealed morphological similarities among fetal ovotestes of tab-1 and Tus-inherited XY sex reversals and BALB/cWt mosaic hermaphrodites. We studied the histology of tda-1 XY sex-reversed gonads, ranging in age from day 14 of gestation to adult. The obtained data revealed additional similarities with ovotestes of BALB/cWt mosaic hermaphrodites as well as with ovotestes of hermaphrodites found in XXsxr and XX/XY chimeras. It is proposed that ovotestes occurring in these various hermaphroditic conditions may be formed through a common pathway. © 1987, International Society of Differentiation. All rights reserved. |
| Keywords: | mouse; phenotype; animal; cytology; mice; embryology; mice, inbred strains; growth, development and aging; ovary; x chromosome; pregnancy; aging; mouse strain; testis; reproduction; y chromosome; cross breeding; crosses, genetic; hermaphroditism; male; female; article; support, u.s. gov't, p.h.s.; sex reversal, gonadal |
| Journal Title: | Differentiation |
| Volume: | 33 |
| Issue: | 3 |
| ISSN: | 0301-4681 |
| Publisher: | International Society of Differentiation |
| Date Published: | 1987-02-01 |
| Start Page: | 214 |
| End Page: | 222 |
| Language: | English |
| DOI: | 10.1111/j.1432-0436.1987.tb01560.x |
| PUBMED: | 3596083 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 5 February 2021 -- Source: Scopus |
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