The acquired immunodeficiency syndrome dementia complex as the presenting or sole manifestation of human immunodeficiency virus infection Journal Article
| Authors: | Navia, B. A.; Price, R. W. |
| Article Title: | The acquired immunodeficiency syndrome dementia complex as the presenting or sole manifestation of human immunodeficiency virus infection |
| Abstract: | Twenty-nine patients at risk of developing acquired immunodeficiency syndrome (AIDS) presented with cognitive, motor, and behavioral dysfunctions characteristic of the AIDS dementia complex, either preceding or in the absence of major systemic opportunistic infections or neoplasms. Six of these patients were medically well, while the remainder suffered only milder manifestations of the AIDS-related complex at the time of their neurologic presentation. Over half of these patients either survived for five to 16 months or died without exhibiting systemic manifestations of AIDS. This experience indicates that the AIDS dementia complex may be the earliest, and, at times, the only evidence of human immunodeficiency infection, and that its development in this context may present a diagnostic challenge, particularly in individuals in whom risk for infection by the AIDS virus is cryptic. © 1987, American Medical Association. All rights reserved. |
| Keywords: | adult; clinical article; aged; case report; classification; tomography, x-ray computed; central nervous system; brain; diagnosis; dementia; human immunodeficiency virus; acquired immune deficiency syndrome; acquired immunodeficiency syndrome; etiology; middle age; human; male; female; priority journal; support, non-u.s. gov't; support, u.s. gov't, p.h.s. |
| Journal Title: | Archives of Neurology |
| Volume: | 44 |
| Issue: | 1 |
| ISSN: | 0003-9942 |
| Publisher: | American Medical Association |
| Date Published: | 1987-01-01 |
| Start Page: | 65 |
| End Page: | 69 |
| Language: | English |
| DOI: | 10.1001/archneur.1987.00520130051017 |
| PUBMED: | 3800724 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 5 February 2021 -- Source: Scopus; Acknowledgements: We thank the patients, their families, and friends who participated in this study, and the physicians who referred patients and assisted in their evaluation. We thank Adele Ahronheim for preparation of this manuscript. |
