Lung cancer Journal Article
| Authors: | Ginsberg, M. S.; Grewal, R. K.; Heelan, R. T. |
| Article Title: | Lung cancer |
| Abstract: | Lung cancer prevention by smoking cessation is an important aspect in discussions on lung cancer. Survival for lung cancer is clearly better for earlier-stage tumors, and whereas it sounds reasonable that early detection in an asymptomatic population is beneficial, there are no definitive data that screening for lung cancer leads to a decrease in mortality. Accurate staging by imaging can have a significant impact on appropriate treatment and surgical options. Staging of newly diagnosed NSCLC is performed according to the International System for Staging Lung Cancer using the TNM system. Because the extent of the disease determines whether the patient is treated by means of surgical resection, radiation therapy, chemotherapy, or a combination of these modalities, radiologic imaging plays an important role in the staging evaluation [90]. SCLC is not staged according to the TNM system but rather as limited-stage disease or extensive-stage disease. Accurate staging by imaging of SCLC is also extremely important. Staging by combined modalities, such as CT and FDG-PET, has been shown to be more accurate than CT or PET alone. Radiologists need to be aware of entire spectrum of manifestations of lung cancer. Familiarity with the different histologic subtypes of lung cancer and the typical and atypical appearances of lung cancer is vital. Radiologists serve a critical role in the diagnosis, staging, and follow-up of patients with NSCLC. This includes suggesting the possibility of synchronous and metachronous lung cancers because it has serious implications in the staging and prognosis of these patients. © 2006 Elsevier Inc. All rights reserved. |
| Keywords: | cancer survival; treatment outcome; aged; aged, 80 and over; middle aged; cancer surgery; clinical trial; review; cigarette smoking; postoperative period; cancer staging; nuclear magnetic resonance imaging; positron emission tomography; follow up; follow-up studies; magnetic resonance imaging; lymph node metastasis; cancer diagnosis; cancer incidence; lymphatic metastasis; neoplasm staging; diagnostic accuracy; sensitivity and specificity; radiopharmaceuticals; metastasis; computer assisted tomography; lung non small cell cancer; carcinoma, non-small-cell lung; lung neoplasms; differential diagnosis; incidence; risk factors; cancer screening; lung cancer; tomography, x-ray computed; biopsy; cancer mortality; time factors; cell type; pneumonia; radiography, thoracic; lung small cell cancer; lung adenocarcinoma; computer assisted diagnosis; cancer cytodiagnosis; early diagnosis; fluorodeoxyglucose f18; positron-emission tomography; lung; brachytherapy; intermethod comparison; atelectasis; pleura effusion; thorax radiography; external beam radiotherapy; cancer classification; lung surgery; sex factors; mediastinum; false positive result; lung fibrosis; sarcoidosis; multiple cancer; fluorodeoxyglucose; lymphadenopathy; lung infiltrate; radiation pneumonia; catheter ablation; mucinous carcinoma; diagnosis, computer-assisted; mediastinum lymph node; carcinoma, small cell; lung nodule; pancoast tumor |
| Journal Title: | Radiologic Clinics of North America |
| Volume: | 45 |
| Issue: | 1 |
| ISSN: | 0033-8389 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2007-01-01 |
| Start Page: | 21 |
| End Page: | 43 |
| Language: | English |
| DOI: | 10.1016/j.rcl.2006.10.004 |
| PUBMED: | 17157622 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 18" - "Export Date: 17 November 2011" - "CODEN: RCNAA" - "Source: Scopus" |
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