What is quality of life in children with bone sarcoma? Journal Article
| Authors: | Frances, J. M.; Morris, C. D.; Arkader, A.; Nikolic, Z. G.; Healey, J. H. |
| Article Title: | What is quality of life in children with bone sarcoma? |
| Abstract: | Quality of life measures have neglected to include a critical self-assessment component in pediatric sarcoma patients. Our report shows how children rate their own quality of life and how that varies over time after surgery. Using the Pediatric Outcomes Data Collection Instrument, quality of life data was prospectively collected and combined with a retrospective review of clinical parameters on 43 children with primary bone sarcoma, with an average followup of 3 years. Children reported good yet variable scores in five of the six domains. Lower scores were noted in the Sports/Physical Functioning domain, particularly in the first 12 months after surgery, with improvement seen up to 24 months after surgery. Tumor specific factors such as size larger than 8 cm and lower extremity location were negative predictors for Sports/Physical Functioning. The only demographic factor that predicted perceived quality of life scores was gender, with girls reporting lower scores in Sports/Physical Functioning, Pain/Comfort, and Global Functioning domains. The Pediatric Outcomes Data Collection Instrument gives discriminatory detailed textured evaluation of the outcome of children treated for skeletal sarcoma. Further development of quality of life measures is needed to allow its use in treatment selection. © 2007 Lippincott Williams & Wilkins, Inc. |
| Keywords: | osteosarcoma; adolescent; child; controlled study; treatment outcome; bone neoplasms; bone tumor; recovery of function; retrospective studies; major clinical study; clinical feature; conference paper; follow up; prospective study; quality of life; cohort studies; tumor volume; cohort analysis; pathology; retrospective study; time; time factors; sarcoma; psychological aspect; health status; self concept; convalescence; pediatrics; sport |
| Journal Title: | Clinical Orthopaedics and Related Research |
| Volume: | 459 |
| ISSN: | 0009-921X |
| Publisher: | Springer |
| Date Published: | 2007-06-01 |
| Start Page: | 34 |
| End Page: | 39 |
| Language: | English |
| DOI: | 10.1097/BLO.0b013e31804f545d |
| PUBMED: | 17353800 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 7" - "Export Date: 17 November 2011" - "CODEN: CORTB" - "Source: Scopus" |
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