Multinational Association of Supportive Care in Cancer (MASCC) 2020 clinical practice recommendations for the management of immune-mediated cardiovascular, rheumatic, and renal toxicities from checkpoint inhibitors Review

  

Authors:	Suarez-Almazor, M. E.; Pundole, X.; Abdel-Wahab, N.; Johnson, D. B.; Gupta, D.; Glezerman, I.; Cooksley, T.; Anderson, R.; Blidner, A.; Choi, J.; Dougan, M.; Ginex, P.; Girotra, M.; Shannon, V. R.; Rapoport, B. L.
Review Title:	Multinational Association of Supportive Care in Cancer (MASCC) 2020 clinical practice recommendations for the management of immune-mediated cardiovascular, rheumatic, and renal toxicities from checkpoint inhibitors
Abstract:	Immune checkpoint inhibitors (ICIs) have emerged as the newest pillar of cancer treatment. Immune-mediated toxicities, stemming from increased activity within the T cell lineage, range from asymptomatic or mild complications to those that are fulminant and potentially fatal. Although they are of variable occurrence, cardiovascular, rheumatic, and renal immune-mediated toxicities are among the most serious of these adverse events. We present MASCC recommendations with respect to the workup and management of cardiovascular, rheumatic, and renal immune-mediated toxicities with a focus on presentations that require treatment with immunomodulating agents. © 2020, Springer-Verlag GmbH Germany, part of Springer Nature.
Keywords:	arthralgia; arthritis; cardiomyopathy; myositis; corticosteroids; myocarditis; immunomodulation agents; other immunosuppressive agents; polymyalgia
Journal Title:	Supportive Care in Cancer
Volume:	28
Issue:	12
ISSN:	0941-4355
Publisher:	Springer Verlag
Date Published:	2020-12-01
Start Page:	6159
End Page:	6173
Language:	English
DOI:	10.1007/s00520-020-05710-8
PUBMED:	32856212
PROVIDER:	scopus
DOI/URL:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85089896593&doi=10.1007%2fs00520-020-05710-8&partnerID=40&md5=c9dcca0ec46b79ce34712dcb83943e68
Notes:	Article -- Export Date: 1 December 2020 -- Source: Scopus

https://synapse.mskcc.org/synapse/works/has_related_data_chk/173395