Hematologic malignancies Book Section

  


Authors: Gupta, M.; Latcha, S.
Editors: Finkel, K. W.; Perazella, M. A.; Cohen, E. P.
Article/Chapter Title: Hematologic malignancies
Abstract: Overall, the reported incidence of paraneoplastic glomerulopathy (PNGN) related to hematologic malignancies is quite rare, with the total number of case reports in the literature only slightly in excess of 200. When compared to myeloid neoplasias, PNGN has been reported relatively more frequently in patients with the lymphoid malignancies, specifically Hodgkin lymphoma (HL), non-Hodgkin lymphoma and chronic lymphocytic leukemia (CLL). Among the lymphoid neoplasia, paraneoplastic minimal change disease and focal segmental glomerular sclerosis (FSGS) are more frequently reported with diseases of the T-cell lineage like HL, whereas paraneoplastic membranoproliferative glomerulonephritis and membranous nephropathy are more commonly reported with B-cell lineage tumors like CLL. Among myeloid malignancies, mesangioproliferative glomerulonephritis is the lesion most commonly reported on renal biopsy, followed by FSGS. The pathogenesis of PNGN with the hematologic malignancies remains poorly defined. © 2020 Elsevier Inc. All rights reserved.
Keywords: hematologic malignancy; proteinuria; myeloid neoplasia; paraneoplastic glomerulopathy; focal segmental glomerulosclerosis; membranous nephropathy; lymphoid neoplasia; cancer and kidney; mesangioproliferative glomerulopathy; minimal change disease
Book Title: Onco-Nephrology
ISBN: 9780323549455
Publisher: Elsevier Inc.  
Publication Place: Philadelphia, PA
Date Published: 2020-01-01
Start Page: 219
End Page: 224.e3
Language: English
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85093479592&doi=10.1016%2fB978-0-323-54945-5.00032-1&partnerID=40&md5=1f84dfa00ff645ae76c781363f06cefa
Notes: Book Chapter: 23 -- Export Date: 2 November 2020 -- Source: Scopus