The potential utility of integrated reflectance confocal microscopy-optical coherence tomography for guiding triage and therapy of basal cell carcinomas Journal Article

   


Authors: Iftimia, N.; Sahu, A.; Cordova, M.; Maguluri, G.; Gill, M.; Alessi-Fox, C.; Gonzalez, S.; Navarrete-Dechent, C.; Marghoob, A.; Chen, C. S. J.; Rajadhyaksha, M.
Article Title: The potential utility of integrated reflectance confocal microscopy-optical coherence tomography for guiding triage and therapy of basal cell carcinomas
Abstract: The increasing rate of incidence and prevalence of basal cell carcinomas (BCCs) worldwide, combined with the morbidity associated with conventional surgical treatment has led to the development and use of alternative minimally invasive non-surgical treatments. Biopsy and pathology are used to guide BCC diagnosis and assess margins and subtypes, which then guide the decision and choice of surgical or non-surgical treatment. However, alternatively, a noninvasive optical approach based on combined reflectance confocal microscopy (RCM) and optical coherence tomography (OCT) imaging may be used. Optical imaging may be used to guide diagnosis and margin assessment at the bedside, and potentially facilitate non-surgical management, along with long-term monitoring of treatment response. Noninvasive imaging may also complement minimally invasive treatments and help further reduce morbidity. In this paper, we highlight the current state of an integrated RCM/OCT imaging approach for diagnosis and triage of BCCs, as well as for assessing margins, which therefore may be ultimately used for guiding therapy. © 2020 Ivyspring International Publisher. All rights reserved.
Keywords: reflectance confocal microscopy; basal cell carcinomas; optical coherence tomography; invasive non-surgical treatments
Journal Title: Journal of Cancer
Volume: 11
Issue: 20
ISSN: 1837-9664
Publisher: Ivyspring International Publisher  
Date Published: 2020-01-01
Start Page: 6019
End Page: 6024
Language: English
DOI: 10.7150/jca.47026
PROVIDER: scopus
PMCID: PMC7477415
PUBMED: 32922542
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85090792346&doi=10.7150%2fjca.47026&partnerID=40&md5=2157f8b717ece74bed48dda94eca6120
Notes: Source: Scopus
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MSK Authors
  1. Chih-Shan Jason Chen
    55 Chen
  2. Ashfaq A Marghoob
    534 Marghoob
  3. Milind Rajadhyaksha
    223 Rajadhyaksha
  4. Miguel A Cordova
    88 Cordova
  5. Aditi Kamlesh Sahu
    30 Sahu
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