Preoperative and adjuvant chemotherapy in locally advanced non-small cell lung cancer Journal Article


Authors: Kris, M. G.; Gralla, R. J.; Martini, N.; Stampleman, L. V.; Burke, M. T.
Article Title: Preoperative and adjuvant chemotherapy in locally advanced non-small cell lung cancer
Abstract: The continued favorable results with surgery in early stage lung cancer have led many investigators to use radiation and chemotherapy to reduce the size of unresectable tumors either before or after definitive surgery. Although earlier results with both radiation and chemotherapy have been poor, the newer cisplatin-containing combination chemotherapy regimens have yielded decreased local recurrence rates when used postoperatively following a complete resection and have produced increased complete resection rates when given preoperatively to patients with locally advanced and unresectable non-small cell lung cancer at diagnosis.
Keywords: review; cisplatin; fluorouracil; lung non small cell cancer; lung cancer; ifosfamide; vinblastine; adjuvant chemotherapy; mitomycin c; vindesine; human
Journal Title: Hematology/Oncology Clinics of North America
Volume: 2
Issue: 3
ISSN: 0889-8588
Publisher: Elsevier Inc.  
Date Published: 1988-09-01
Start Page: 407
End Page: 415
Language: English
DOI: 10.1016/s0889-8588(18)30604-x
PROVIDER: scopus
DOI/URL:
Notes: Article -- Source: Scopus
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  1. Mark Kris
    869 Kris
  2. Nael   Martini
    105 Martini
  3. Richard J. Gralla
    69 Gralla