Authors: | Budde‐Steffen, C.; Anderson, N. E.; Rosenblum, M. K.; Graus, F.; Ford, D.; Synek, B. J. L.; Wray, S. H.; Posner, J. B. |
Article Title: | An antineuronal autoantibody in paraneoplastic opsoclonus |
Abstract: | Sera from 7 patients with paraneoplastic opsoclonus were examined for antineuronal autoantibodies. An antibody against neuronal nuclei was found in serum from a patient with breast cancer, opsoclonus, and ataxia. This antibody recognized 53‐ to 61‐kDa and 79‐ to 84‐kDa antigens in immunoblots of neurons. Anti‐neuronal antibodies were not found in other patients with paraneoplastic opsoclonus. Copyright © 1988 American Neurological Association |
Keywords: | adult; case report; cerebellum; neurons; breast neoplasms; monoclonal antibody; infant; carcinoma; ganglioside gm1; molecular weight; autoantibodies; ganglioside gd 1b; immunoglobulin m; middle age; motor neuron disease; paraneoplastic syndromes; human; male; female; priority journal; support, non-u.s. gov't; eye movements |
Journal Title: | Annals of Neurology |
Volume: | 23 |
Issue: | 5 |
ISSN: | 0364-5134 |
Publisher: | Wiley Blackwell |
Date Published: | 1988-05-01 |
Start Page: | 528 |
End Page: | 531 |
Language: | English |
DOI: | 10.1002/ana.410230518 |
PUBMED: | 3389761 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | Article -- Export Date: 6 August 2020 -- Source: Scopus |