An antineuronal autoantibody in paraneoplastic opsoclonus Journal Article

  


Authors: Budde‐Steffen, C.; Anderson, N. E.; Rosenblum, M. K.; Graus, F.; Ford, D.; Synek, B. J. L.; Wray, S. H.; Posner, J. B.
Article Title: An antineuronal autoantibody in paraneoplastic opsoclonus
Abstract: Sera from 7 patients with paraneoplastic opsoclonus were examined for antineuronal autoantibodies. An antibody against neuronal nuclei was found in serum from a patient with breast cancer, opsoclonus, and ataxia. This antibody recognized 53‐ to 61‐kDa and 79‐ to 84‐kDa antigens in immunoblots of neurons. Anti‐neuronal antibodies were not found in other patients with paraneoplastic opsoclonus. Copyright © 1988 American Neurological Association
Keywords: adult; case report; cerebellum; neurons; breast neoplasms; monoclonal antibody; infant; carcinoma; ganglioside gm1; molecular weight; autoantibodies; ganglioside gd 1b; immunoglobulin m; middle age; motor neuron disease; paraneoplastic syndromes; human; male; female; priority journal; support, non-u.s. gov't; eye movements
Journal Title: Annals of Neurology
Volume: 23
Issue: 5
ISSN: 0364-5134
Publisher: Wiley Blackwell  
Date Published: 1988-05-01
Start Page: 528
End Page: 531
Language: English
DOI: 10.1002/ana.410230518
PUBMED: 3389761
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023939488&doi=10.1002%2fana.410230518&partnerID=40&md5=e7a4f634f3257ddd9887988203d77b97
Notes: Article -- Export Date: 6 August 2020 -- Source: Scopus
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MSK Authors
  1. Marc Rosenblum
    424 Rosenblum
  2. Jerome B Posner
    211 Posner
  3. Neil E. Anderson
    15 Anderson
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