Flow cytometry in cytopathology: Overview and perspectives Journal Article


Author: Darzynkiewicz, Z.
Article Title: Flow cytometry in cytopathology: Overview and perspectives
Abstract: The future applications of flow cytometry (FCM) are briefly discussed. Whereas the early goals of its clinical applications were cancer diagnosis and classification, it has now become apparent that FCM can more successfully provide information on a variety of cell constituents of crucial importance in the evaluation of tumor prognosis and treatment sensitivity. It is suggested that (1) the data being provided by FCM will probably lead to a more clinically relevant classification of tumors, based more on the biochemical/molecular markers of individual cells and an assessment of tumor heterogeneity and less on classical cell morphology and tumor progression, and (2) FCM seems likely to become established as a routine methodology in cytopathology.
Keywords: flow cytometry; methodology; cancer diagnosis; cytology; pathology; short survey; cytopathology; cytological techniques; human; support, u.s. gov't, p.h.s.
Journal Title: Analytical and Quantitative Cytology and Histology
Volume: 10
Issue: 6
ISSN: 0884-6812
Publisher: Science Printers and Publishers, Inc.  
Date Published: 1988-12-01
Start Page: 459
End Page: 461
Language: English
PUBMED: 3064765
PROVIDER: scopus
DOI/URL:
Notes: Review -- Export Date: 6 August 2020 -- Source: Scopus
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