Neuropsychological characterization of the AIDS dementia complex: A preliminary report Journal Article


Authors: Tross, S.; Price, R. W.; Navia, B.; Thaler, H. T.; Gold, J.; Hirsch, D. A.; Sidtis, J. J.
Article Title: Neuropsychological characterization of the AIDS dementia complex: A preliminary report
Abstract: The AIDS dementia complex (ADC) is a frequent complication of advanced HIV infection. In order to better define the neuropsychological character and progression of the ADC, four groups of subjects were studied with a battery of neuropsychological tests: an HIV-seronegative comparison group (n = 20), asymptomatic HIV-seropositive patients (n = 16), newly diagnosed AIDS patients (n = 44) and AIDS patients who were referred for neurological consultation (n = 40). Results showed significant reductions in performance in the two AIDS groups, with impairment being most prominent in tests that assessed motor speed and fine control, concentration, problem solving and visuospatial performance. This pattern of neuropsychological dysfunction is consistent with the characterization of the ADC as a subcortical dementia.
Keywords: clinical article; human cell; psychology; psychological aspect; dementia; acquired immune deficiency syndrome; psychologic test; human immunodeficiency virus 1; aids related complex; human; priority journal; preliminary communication
Journal Title: AIDS
Volume: 2
Issue: 2
ISSN: 0269-9370
Publisher: Lippincott Williams & Wilkins  
Date Published: 1988-04-01
Start Page: 81
End Page: 88
Language: English
DOI: 10.1097/00002030-198804000-00002
PUBMED: 3132951
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 6 August 2020 -- Source: Scopus
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
  1. Howard T Thaler
    245 Thaler
  2. Jonathan W. M. Gold
    73 Gold
  3. Susan Tross
    16 Tross
  4. Richard W. Price
    58 Price
  5. John J. Sidtis
    18 Sidtis