Rubbing out leukemia stem cells by erasing the eraser Journal Article

   


Authors: Cheng, Y.; Luo, H.; Kharas, M. G.
Article Title: Rubbing out leukemia stem cells by erasing the eraser
Abstract: In this issue of Cell Stem Cell, Shen et al. (2020) and Wang et al. (2020) independently identify the essential function of m6A demethylase ALKBH5 in maintaining myeloid leukemia stem cells. These studies expand the regulators of the epitranscriptome that are required for acute myeloid leukemia (AML) development. © 2020 Elsevier Inc. In this issue of Cell Stem Cell, Shen et al. (2020) and Wang et al. (2020) independently identify the essential function of m6A demethylase ALKBH5 in maintaining myeloid leukemia stem cells. These studies expand the regulators of the epitranscriptome that are required for acute myeloid leukemia (AML) development. © 2020 Elsevier Inc.
Keywords: promoter region; nonhuman; protein function; gene expression; leukemogenesis; cancer stem cell; upregulation; rna methylation; acute myeloid leukemia; cancer prognosis; gene knockdown; human; priority journal; article; rna sequencing; stem cell self-renewal; clustered regularly interspaced short palindromic repeat; 6 n methyladenosine; alkylated dna repair protein alkb homolog 5
Journal Title: Cell Stem Cell
Volume: 27
Issue: 1
ISSN: 1934-5909
Publisher: Cell Press  
Date Published: 2020-07-02
Start Page: 3
End Page: 5
Language: English
DOI: 10.1016/j.stem.2020.06.009
PUBMED: 32619516
PROVIDER: scopus
PMCID: PMC9310347
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85087025400&doi=10.1016%2fj.stem.2020.06.009&partnerID=40&md5=017cd4f23bf4811f71a3a223b2ef46b7
Notes: Article -- Export Date: 3 August 2020 -- Source: Scopus
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MSK Authors
  1. Michael Kharas
    96 Kharas
  2. Yuanming Cheng
    11 Cheng
  3. Hanzhi Luo
    22 Luo
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