Diffusion-weighted echo planar imaging using multiplexed sensitivity encoding and reverse polarity gradient in head and neck cancer: An initial study Journal Article
| Authors: | Konar, A. S.; Fung, M.; Paudyal, R.; Oh, J. H.; Mazaheri, Y.; Hatzoglou, V.; Shukla-Dave, A. |
| Article Title: | Diffusion-weighted echo planar imaging using multiplexed sensitivity encoding and reverse polarity gradient in head and neck cancer: An initial study |
| Abstract: | We aimed to compare the geometric distortion (GD) correction performance and apparent diffusion coefficient (ADC) measurements of single-shot diffusion-weighted echo-planar imaging (SS-DWEPI), multiplexed sensitivity encoding (MUSE)-DWEPI, and MUSE-DWEPI with reverse-polarity gradient (RPG) in phantoms and patients. We performed phantom studies at 3T magnetic resonance imaging (MRI) using the American College of Radiology phantom and Quantitative Imaging Biomarker Alliance DW-MRI ice-water phantom to assess GD and effect of distortion in the measurement of ADC, respectively. Institutional review board approved the prospective clinical component of this study. DW-MRI data were obtained from 11 patients with head and neck cancer using these three DW-MRI methods. Wilcoxon signed-rank (WSR) and Kruskal-Wallis (KW) tests were used to compare ADC values, and qualitative rating by radiologist between three DW-MRI methods. In the ACR phantom, GD of 0.17% was observed for the b = 0 s/mm2 image of the MUSE-DWEPI with RPG method compared with that of 1.53% and 2.1% of MUSE-DWEPI and SS-DWEPI, respectively; The corresponding methods root-mean-square errors were 0.58, 3.37, and 5.07 mm. WSR and KW tests showed no significant difference in the ADC measurement between these three DW-MRI methods for both healthy masseter muscles and neoplasms (P > .05). We observed improvement in spatial accuracy for MUSE-DWEPI with RPG in the head and neck region with a higher correlation (R2 = 0.791) compared with that for SS-DWEPI (R2 = 0.707) and MUSE-DWEPI (R2 = 0.745). MUSE-DWEPI with RPG significantly reduces the distortion compared with MUSE-DWEPI or conventional SS-DWEPI techniques, and the ADC values were similar. © 2020 The Authors. Published by Grapho Publications, LLC. |
| Keywords: | diffusion-weighted mri; echo planar imaging; eddy current; geometrical distortion; head and neck region; magnetic field inhomogeneity; multiplexed sensitivity encoding; reverse-polarity gradients |
| Journal Title: | Tomography |
| Volume: | 6 |
| Issue: | 2 |
| ISSN: | 2379-1381 |
| Publisher: | MDPI |
| Date Published: | 2020-06-01 |
| Start Page: | 231 |
| End Page: | 240 |
| Language: | English |
| DOI: | 10.18383/j.tom.2020.00014 |
| PUBMED: | 32548301 |
| PROVIDER: | scopus |
| PMCID: | PMC7289242 |
| DOI/URL: | |
| Notes: | Article -- Source: Scopus |
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