Authors: | Crompton, J. G.; Busam, K. J.; Bartlett, E. K. |
Review Title: | Interpretation of the complex melanoma pathology report |
Abstract: | An ambiguous pathologic report can present a clinical dilemma to the treating surgeon. We describe lesions ranging from the potentially benign to the likely malignant. Correctly identifying features associated with higher-risk lesions has proven challenging given the overall good prognosis and low rate of events. An appropriate treatment plan generally requires discussion between the surgeon and an experienced dermatopathologist. When clinically indicated, additional testing may be used to further support or refute a diagnosis of melanoma. The indications for these techniques, the data to support their use, and the strengths and weakness of each are reviewed. © 2020 Elsevier Inc. |
Keywords: | immunohistochemistry; clinical feature; review; cancer recurrence; melanoma; gene expression; cytogenetics; mutational analysis; risk factor; fluorescence in situ hybridization; melanocytic nevus; cancer classification; genomic in situ hybridization; human; molecular dermatopathology; atypical melanocytic proliferations |
Journal Title: | Surgical Oncology Clinics of North America |
Volume: | 29 |
Issue: | 3 |
ISSN: | 1055-3207 |
Publisher: | Elsevier Inc. |
Date Published: | 2020-07-01 |
Start Page: | 327 |
End Page: | 338 |
Language: | English |
DOI: | 10.1016/j.soc.2020.02.013 |
PUBMED: | 32482311 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | Review -- Source: Scopus |