Optimal management of gastric cancer: Results from an international RAND/UCLA expert panel Journal Article


Authors: Coburn, N.; Seevaratnam, R.; Paszat, L.; Helyer, L.; Law, C.; Swallow, C.; Cardosa, R.; Mahar, A.; Lourenco, L. G.; Dixon, M.; Bekaii-Saab, T.; Chau, I.; Church, N.; Coit, D.; Crane, C. H.; Earle, C.; Mansfield, P.; Marcon, N.; Miner, T.; Noh, S. H.; Porter, G.; Posner, M. C.; Prachand, V.; Sano, T.; van de Velde, C.; Wong, S.; McLeod, R.
Article Title: Optimal management of gastric cancer: Results from an international RAND/UCLA expert panel
Abstract: OBJECTIVE: Defining processes of care, which are appropriate and necessary for management of gastric cancer (GC), is an important step toward improving outcomes. METHODS: Using a RAND/UCLA Appropriateness Method, an international multidisciplinary expert panel created 22 statements reflecting optimal management. All statements were scored for appropriateness and necessity. RESULTS: The following tenets were scored appropriate and necessary: (1) preoperative staging by computed tomography of abdomen/pelvis; (2) positron-emission tomographic scans not routinely indicated; (3) consideration for adjuvant therapy; (4) further clinical trials; (5) multidisciplinary decision making; (6) sufficient support at hospitals; (7) assessment of 16 or more lymph nodes (LNs); (8) in metastatic disease, surgery only for palliation of major symptoms; (9) surgeons experienced in GC management; (10) and surgeons experienced in both GC management and advanced laparoscopic surgery for laparoscopic resection. The following were scored appropriate, but of indeterminate necessity: (1) diagnostic laparoscopy before treatment; (2) a multidisciplinary approach to linitis plastica; (3) genetic assessment for diffuse GC and family history, or age less than 45 years; (4) endoscopic removal of select T1aN0 lesions; (5) D2 LN dissection in curative intent cases; (6) D1 LN dissection for early GC or patients with comorbidities; (7) frozen section analysis of margins; (8) nonemergent cases performed in a hospital with a volume of more than 15 resections per year; and (9) by a surgeon with more than 6 resection per year. CONCLUSIONS: The expert panel has created 22 statements for the perioperative management of GC patients, to provide guidance to clinicians and improve the care received by patients. Copyright © 2013 by Lippincott Williams & Wilkins.
Keywords: management; stomach; gastric; cancer
Journal Title: Annals of Surgery
Volume: 259
Issue: 1
ISSN: 0003-4932
Publisher: Lippincott Williams & Wilkins  
Date Published: 2014-01-01
Start Page: 102
End Page: 108
Language: English
DOI: 10.1097/SLA.0b013e318288dd2b
PROVIDER: scopus
PUBMED: 23478525
DOI/URL:
Notes: Export Date: 3 February 2014 -- CODEN: ANSUA -- Source: Scopus
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  1. Daniel Coit
    542 Coit