Bulbar encephalitis complicating trigeminal zoster in the acquired immune deficiency syndrome Journal Article
| Author: | Rosenblum, M. K. |
| Article Title: | Bulbar encephalitis complicating trigeminal zoster in the acquired immune deficiency syndrome |
| Abstract: | A 30-year-old homosexual man with the acquired immune deficiency syndrome and a recent history of zoster involving the mandibular division of the right trigeminal nerve was found at autopsy to have a predominantly demyelinating lesion restricted to the ipsilateral spinal trigeminal tract and nucleus. Cowdry A inclusions were readily apparent in the nuclei of numerous glia and isolated neurons, and inclusion-bearing cells were immunoreactive with an antiserum to the varicella zoster virus (VZV). This represents the first demonstration that zoster-associated trigeminal encephalitis is the result of brainstem invasion by VZV. The restricted topography of this lesion implicates axonal transport in its pathogenesis. © 1989. |
| Keywords: | adult; human cell; case report; herpes zoster; histology; spinal cord; acquired immune deficiency syndrome; acquired immunodeficiency syndrome; autopsy; encephalitis; brain stem; aids; varicella zoster virus; trigeminal nerve; cranial nerve diseases; human; male; priority journal; varicella zoster |
| Journal Title: | Human Pathology |
| Volume: | 20 |
| Issue: | 3 |
| ISSN: | 0046-8177 |
| Publisher: | Elsevier Inc. |
| Date Published: | 1989-03-01 |
| Start Page: | 292 |
| End Page: | 295 |
| Language: | English |
| DOI: | 10.1016/0046-8177(89)90140-8 |
| PUBMED: | 2722178 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 14 April 2020 -- Source: Scopus |
