Contralateral prophylactic mastectomy in breast cancer: What to discuss with patients Review


Authors: Montagna, G.; Morrow, M.
Review Title: Contralateral prophylactic mastectomy in breast cancer: What to discuss with patients
Abstract: Introduction: The contralateral prophylactic mastectomy (CPM) rate in the U.S. has been steadily increasing. This is of particular concern because many women who undergo this procedure are candidates for breast-conserving surgery. Areas covered: CPM’s medical benefit is related to the risk of contralateral cancer development and whether CPM provides a survival benefit. Contralateral cancer rates have decreased, and CPM does not provide a survival benefit. Other potential benefits of the procedure may be improved quality of life; these data are reviewed. Research efforts have been undertaken to better understand the decision-making process of patients who consider, and ultimately undergo, this procedure. Expert opinion: Decisional traits, personal values, the desire for peace of mind, and the desire to obtain breast symmetry are important factors that drive a woman’s decision to undergo CPM. Additionally, many patients lack the knowledge on how different types of breast surgery impact outcomes. To improve the shared decision-making process, a stepwise approach to address possible misconceptions, and clarify the real risks/benefits of this procedure should be utilized. A clear recommendation (for/against) should be made for every patient with newly diagnosed breast cancer who considers CPM. Communication tools to assist patients and surgeons in this process are sorely needed. © 2020, © 2020 Informa UK Limited, trading as Taylor & Francis Group.
Keywords: patient education; contralateral prophylactic mastectomy; shared decision making; benefits; harms
Journal Title: Expert Review of Anticancer Therapy
Volume: 20
Issue: 3
ISSN: 1473-7140
Publisher: Taylor & Francis Group  
Date Published: 2020-01-01
Start Page: 159
End Page: 166
Language: English
DOI: 10.1080/14737140.2020.1732213
PUBMED: 32077338
PROVIDER: scopus
PMCID: PMC7193761
DOI/URL:
Notes: Review -- Export Date: 1 April 2020 -- Source: Scopus
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  1. Monica Morrow
    772 Morrow
  2. Giacomo Montagna
    100 Montagna