Clinical characteristics and disease course in black patients with lymphomatoid papulosis: A case series Journal Article
| Authors: | Geller, S.; Noor, S. J.; Myskowski, P. L. |
| Article Title: | Clinical characteristics and disease course in black patients with lymphomatoid papulosis: A case series |
| Abstract: | Introduction: Lymphomatoid papulosis (LyP) is a CD30+ T-cell lymphoproliferative disorder (LPD) presenting as a recurrent eruption of papules and nodules which resolve spontaneously. CD30+ LPD prevalence in African American (AA)/Black patients is lower compared to White patients. CD30+ LPD has been recently reported to have worse outcomes in AA patients compared to White patients. Methods: A retrospective chart review identified eight AA patients with LyP. We describe our experience with these eight patients and review the literature on similar cases. Results: In half of the eight included patients, lesions occurred 1-4 years before they were diagnosed. In six patients (75%), resolution of the lesions resulted in hyperpigmented macules and scars. Five patients (63%) had also mycosis fungoides. Most of the patients who were followed (4/7, 57%) did not have complete resolution at their last visit, despite different treatment approaches. Discussion: Our results highlight that although LyP has an indolent course in AA/Black patients, residual hyperpigmentation and scars frequently occur, highlighting the need for better treatments of this lymphoproliferative disorder in this specific population. |
| Keywords: | brentuximab vedotin |
| Journal Title: | Journal of Drugs in Dermatology |
| Volume: | 19 |
| Issue: | 1 |
| ISSN: | 1545-9616 |
| Publisher: | Journal of Drugs in Dermatology, Inc. |
| Date Published: | 2020-01-01 |
| Start Page: | 89 |
| End Page: | 91 |
| Language: | English |
| ACCESSION: | WOS:000508286700011 |
| DOI: | 10.36849/jdd.2020.4602 |
| PROVIDER: | wos |
| PUBMED: | 32023015 |
| Notes: | Source: Wos |
Altmetric
Citation Impact
BMJ Impact Analytics
Related MSK Work