An ELISA-inhibition assay for antibody to human immunodeficiency virus core antigen (p24) Journal Article
| Authors: | Povolotsky, J.; Gold, J. W. M.; Darminin, P.; Chein, N.; Baron, P.; Armstrong, D. |
| Article Title: | An ELISA-inhibition assay for antibody to human immunodeficiency virus core antigen (p24) |
| Abstract: | An ELISA-inhibition assay based on commercially available HIV-1 p24 antigen tests was developed for detecting p24 antibodies. The test is specific and simple. p24 antibody was detectable in all p24 antigen negative Western blot positive sera, but was detectable infrequently in antigen positive sera. Sera from patients with indeterminate HIV-1 reactions (individuals without evidence of HIV-1 infection who nevertheless had p24 antibody) were p24 antigen negative and p24 antibody negative in the ELISA-inhibition reaction. © 1990. |
| Keywords: | major clinical study; nonhuman; comparative study; enzyme linked immunosorbent assay; blotting, western; immune response; virus antigen; human immunodeficiency virus; acquired immune deficiency syndrome; acquired immunodeficiency syndrome; virus infection; enzyme-linked immunosorbent assay; immune deficiency; human immunodeficiency virus 1; hiv-1; hiv seropositivity; gene products, gag; hiv antibodies; reagent kits, diagnostic; human; priority journal; article; hiv antigens; virus core; viral core proteins; hiv core protein p24; hiv-1 p24 antibody; hiv-1 p24 antigen |
| Journal Title: | Journal of Virological Methods |
| Volume: | 30 |
| Issue: | 1 |
| ISSN: | 0166-0934 |
| Publisher: | Elsevier BV |
| Date Published: | 1990-10-01 |
| Start Page: | 109 |
| End Page: | 114 |
| Language: | English |
| DOI: | 10.1016/0166-0934(90)90048-k |
| PUBMED: | 2128300 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 27 January 2020 -- Source: Scopus |
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