Postoperative radiation therapy for major salivary gland malignancies Journal Article
| Authors: | Harrison, L. B.; Armstrong, J. G.; Spiro, R. H.; Fass, D. E.; Strong, E. W. |
| Article Title: | Postoperative radiation therapy for major salivary gland malignancies |
| Abstract: | Between 1966 and 1982 there have been 46 patients treated with surgery plus post‐operative radiation therapy for malignant tumors of salivary gland origin. The indication(s) for radiotherapy included positive margins (42%), advanced local tumor (37%), positive nodes (33%), or high grade histology (48%). Overall actuarial local control at 5 years was 73%, being 100% for T1, 83% for T2, 80% for T3, and 43% for T4. Actuarial survival at 5 years was 80% for T1, 83% for T2 60% for T3 and 48% for T4. Patients with positive nodes (N+) did worse than those with negative nodes (No), with locoregional control and survival at 5 years being 58% vs. 83%, ( P=0.025) and 38% vs. 80% (P=<.01), respectively. We found no need for contralateral neck treatment even for those with positive nodes. Also, to date, none of eight patients with adenoid cystic histology has failed locally, as opposed to three of eight failures in patients treated with surgery alone. We believe that post‐operative irradiation provides excellent locoregional control for appropriate patients with malignant tumors of major salivary glands. Copyright © 1990 Wiley‐Liss, Inc., A Wiley Company |
| Keywords: | adolescent; adult; clinical article; aged; aged, 80 and over; survival rate; postoperative period; lymph node metastasis; lymphatic metastasis; neoplasm staging; radiotherapy dosage; salivary gland tumor; salivary gland neoplasms; neck; local control; carcinoma, adenoid cystic; middle age; nodal involvement; life tables; human; male; female; priority journal; article; survival tumor stage |
| Journal Title: | Journal of Surgical Oncology |
| Volume: | 45 |
| Issue: | 1 |
| ISSN: | 0022-4790 |
| Publisher: | Wiley Blackwell |
| Date Published: | 1990-09-01 |
| Start Page: | 52 |
| End Page: | 55 |
| Language: | English |
| DOI: | 10.1002/jso.2930450112 |
| PUBMED: | 2166187 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 27 January 2020 -- Source: Scopus |
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