Polyradiculopathy in leptomeningeal metastasis: The role of EMG and late response studies Journal Article


Authors: Kaplan, J. G.; Portenoy, R. K.; Pack, D. R.; DeSouza, T.
Article Title: Polyradiculopathy in leptomeningeal metastasis: The role of EMG and late response studies
Abstract: Leptomeningeal metastasis (LM) of systemic malignancy often give rise to multifocal involvement of the central (CNS) and peripheral nervous system. Signs of CNS dysfunction such as seizures and confusion often overshadow radicular deficits. We report clinical and laboratory evaluations in 10 patients with LM who presented with isolated polyradiculopathy. Our data suggest that electromyography and late response studies are sensitive indicators of radicular dysfunction in patients with LM. These studies are helpful in the early documentation of root involvement when computerized tomography, MRI and myelography are normal. © 1990 Kluwer Academic Publishers.
Keywords: adolescent; adult; clinical article; aged; meningeal neoplasms; motor neurons; electromyography; peripheral nerves; reflex; carcinomatous meningitis; peripheral nervous system diseases; neurologic examination; polyradiculopathy; middle age; leptomeningeal metastasis; leptomeninx; myelography; nerve conduction studies; neural conduction; nerve conduction; human; male; female; article; emg; polyradiculitis; late response studies
Journal Title: Journal of Neuro-Oncology
Volume: 9
Issue: 3
ISSN: 0167-594X
Publisher: Springer  
Date Published: 1990-12-01
Start Page: 219
End Page: 224
Language: English
DOI: 10.1007/bf02341152
PUBMED: 1964961
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 27 January 2020 -- Source: Scopus
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  1. Russell K. Portenoy
    165 Portenoy