Transcriptional control in hepatocytes: A window on development Journal Article
| Authors: | Lai, E.; Darnell, J. E. Jr |
| Article Title: | Transcriptional control in hepatocytes: A window on development |
| Abstract: | The unique phenotype of each differentiated cell in an animal (or plant) arises from selective expression of genes in a cell- or tissue-specific fashion, which is controlled primarily at the level of transcription. This review will focus on transcription factors that regulate cell-specific transcription in one intensely studied cell type, the hepatocyte or parenchymal liver cell. All of the recently isolated transcription factors that are important in hepatocyte-specific gene expression were identified in adult liver and there are strong hints that some of these may play an important role in embryogenesis. © 1991. |
| Keywords: | dna-binding proteins; review; animal; gene expression; transcription factor; embryo development; animalia; transcription factors; nuclear proteins; gene expression regulation; liver; transcription regulation; development; enhancer elements (genetics); priority journal |
| Journal Title: | Trends in Biochemical Sciences |
| Volume: | 16 |
| Issue: | 11 |
| ISSN: | 0968-0004 |
| Publisher: | Elsevier Inc. |
| Date Published: | 1991-11-01 |
| Start Page: | 427 |
| End Page: | 430 |
| Language: | English |
| DOI: | 10.1016/0968-0004(91)90169-v |
| PUBMED: | 1776173 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Source: Scopus |
