Melanoma mimicking seborrheic keratosis: An error of perception precluding correct dermoscopic diagnosis Journal Article


Authors: Braga, J. C. Tavoloni; Scope, A.; Klaz, I.; Mecca, P.; Spencer, P.; Marghoob, A. A.
Article Title: Melanoma mimicking seborrheic keratosis: An error of perception precluding correct dermoscopic diagnosis
Abstract: Seborrheic keratosis is a common skin lesion that can usually be recognized either clinically or dermoscopically. However, melanomas mimicking seborrheic keratoses, as well as melanomas arising in association with seborrheic keratoses, have been described. We report the case of a patient with a lesion that initially revealed "classic" dermoscopic features of a seborrheic keratosis. However, during follow-up, changes in color developed within the center of the lesion that led the clinician to the correct diagnosis of melanoma. Upon retrospective evaluation of the baseline image of the lesion; the clinician was now able to "see" that which his brain could not appreciate on initial examination and to realize that the lesion had subtle features suspect for melanoma. This case represents a diagnostic pitfall due to errors in perception. Dermatologists should be cognizant of "errors in perception"; we suggest that a final dermoscopic judgment of a seborrheic keratosis be rendered by combining the gestalt diagnosis of the overall pattern, with deliberate dermoscopic analysis of all quadrants of the lesion. © 2008 American Academy of Dermatology, Inc.
Keywords: human tissue; aged; clinical feature; case report; follow up; melanoma; dermoscopy; skin biopsy; skin neoplasms; retrospective study; epiluminescence microscopy; diagnostic errors; head and neck neoplasms; skin examination; diagnostic error; risk reduction; perception; keratosis, seborrheic; seborrheic dermatitis
Journal Title: Journal of the American Academy of Dermatology
Volume: 58
Issue: 5
ISSN: 0190-9622
Publisher: Mosby Elsevier  
Date Published: 2008-05-01
Start Page: 875
End Page: 880
Language: English
DOI: 10.1016/j.jaad.2007.12.011
PUBMED: 18328596
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 8" - "Export Date: 17 November 2011" - "CODEN: JAADD" - "Source: Scopus"
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MSK Authors
  1. Juliana Casagrande Tavoloni Braga
    5 Braga
  2. Itay Klaz
    2 Klaz
  3. Alon Scope
    125 Scope
  4. Ashfaq A Marghoob
    534 Marghoob
  5. Patricia Stella Mecca
    13 Mecca