CT-SPECT fusion for analysis of radiolabeled antibodies: Applications in gastrointestinal and lung carcinoma Conference Paper


Authors: Kramer, E. L.; Noz, M. E.
Title: CT-SPECT fusion for analysis of radiolabeled antibodies: Applications in gastrointestinal and lung carcinoma
Conference Title: 2nd International Conference on Diagnosis and Therapy with Monoclonal Antibodies
Abstract: Fusing or image registration improves the information obtained by correlating images from various imaging modalities. We "fused" radiolabeled antibody SPECT with CT in patients with colorectal or lung cancer. We identified corresponding landmarks on cross-sectional images and used standard graphics algorithms for untilting to match planes of reconstruction and for two-dimensional warping or ransformation of images or regions of interest. Fusing localizes activity on SPECT to specific anatomic structures and decreases SPECT false positives and CT false negatives. © 1991.
Keywords: clinical article; controlled study; conference paper; technetium 99m; colorectal cancer; computer assisted tomography; lung cancer; monoclonal antibody; isotope labeling; single photon emission computer tomography; intravenous drug administration; human; male; female; priority journal
Journal Title International Journal of Radiation Applications and Instrumentation. Part B: Nuclear Medicine and Biology
Volume: 18
Issue: 1
Conference Dates: 1990 Apr 26-28
Conference Location: Naples, Italy
ISBN: 0883-2897
Publisher: Elsevier, Inc.  
Date Published: 1991-01-01
Start Page: 27
End Page: 42
Language: English
DOI: 10.1016/0883-2897(91)90043-k
PUBMED: 2010302
PROVIDER: scopus
DOI/URL:
Notes: Source: Scopus
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