Focal myocardial uptake in a patient with carcinoid tumor by indium-111-pentetreotide on SPECT/CT Journal Article


Authors: Mahmood, S.; Martinez De Llano, S. R.; Grewal, R. K.
Article Title: Focal myocardial uptake in a patient with carcinoid tumor by indium-111-pentetreotide on SPECT/CT
Abstract: We present a case of a 44 year old man with flushing, diarrhea and markedly elevated 24 hour urinary 5-HIAA level, who was referred for an indium-111 pentetreotide study, after the excision of a carcinoid tumor in the terminal ileum. Scan findings revealed focal uptake in the myocardium and liver, suspicious for metastases. Subsequent transthoracic echocardiogram failed to demonstrate a cardiac lesion. Previously, our group has unequivocally demonstrated the usefulness of software fusion of SPECT and CT imaging in the evaluation of a carcinoid metastasizing to the myocardium. This case illustrates that hardware SPECT/CT fusion imaging utilizing indium-111 pentetreotide to evaluate metastatic carcinoid tumors can be useful. In addition, the echocardiogram can yield false negative results, because of a smaller lesion size and the influence of an operator-dependent factor.
Keywords: adult; clinical feature; case report; diarrhea; metastasis; computer assisted tomography; tumor biopsy; flushing; false negative result; indium radioisotopes; drug uptake; carcinoid; single photon emission computer tomography; protein urine level; carcinoid tumor; heart; heart muscle; pentetreotide in 111; somatostatin; transthoracic echocardiography; 5 hydroxyindoleacetic acid; spect/ct; heart tumor; cardiac metastasis; false negative; indium-111 pentetreotide; ileum tumor; carcinoid heart disease
Journal Title: Revista Espanola de Medicina Nuclear
Volume: 27
Issue: 5
ISSN: 0212-6982
Publisher: Elsevier Science Inc.  
Date Published: 2008-09-01
Start Page: 355
End Page: 357
Language: English
DOI: 10.1157/13126192
PUBMED: 18817665
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 1" - "Export Date: 17 November 2011" - "CODEN: REMNE" - "Source: Scopus"
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  1. Ravinder K Grewal
    82 Grewal