Successful management of CMV pneumonia in a mechanically ventilated patient Journal Article

  


Authors: Sommer, S. E.; Emanuel, D.; Groeger, J. S.; Carlon, G. C.
Article Title: Successful management of CMV pneumonia in a mechanically ventilated patient
Abstract: We report a case of severe respiratory failure due to cytomegalovirus pneumonitis in a patient who underwent an allogeneic bone marrow transplant, who was successfully treated with the combination of ganciclovir and high-dose intravenous immune globulin. We also reviewed the rationale for the use of combination therapy with an antiviral agent and immunotherapy. Because of the bone marrow toxicity of ganciclovir, an aggressive diagnostic approach, including bronchoalveolar lavage and open lung biopsy, may be necessary to establish a definitive diagnosis prior to institution of therapy.
Keywords: adult; case report; pneumonia; immunoglobulin g; bone marrow transplantation; ganciclovir; cytomegalovirus infection; intravenous drug administration; artificial ventilation; human; male; priority journal; article
Journal Title: Chest
Volume: 100
Issue: 3
ISSN: 0012-3692
Publisher: American College of Chest Physicians  
Date Published: 1991-09-01
Start Page: 856
End Page: 858
Language: English
DOI: 10.1378/chest.100.3.856
PUBMED: 1653682
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-0025941820&doi=10.1378%2fchest.100.3.856&partnerID=40&md5=550298b1e7854f08e035ff89d4b2c1c7
Notes: Article -- Export Date: 27 September 2019 -- Source: Scopus
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MSK Authors
  1. Jeffrey Groeger
    91 Groeger
  2. Graziano Carlon
    50 Carlon
  3. David J. Emanuel
    28 Emanuel
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