Critical prognostic parameters in the anatomic pathology reporting of differentiated follicular cell-derived thyroid carcinoma Review


Authors: Xu, B.; Ghossein, R.
Review Title: Critical prognostic parameters in the anatomic pathology reporting of differentiated follicular cell-derived thyroid carcinoma
Abstract: In the past decades, pathology reporting on thyroid carcinoma has evolved from a narrative approach to structured synoptic reports. Many histologic variables are present in the current synoptic reports that are crucial elements for initial risk stratification and clinical management. In this review, we compare and summarize the key prognostic pathologic characteristics utilized by the most influential clinical and pathologic guidelines from the American Thyroid Association (ATA), the National Comprehensive Cancer Network (NCCN), the current World Health Organization (WHO) classification of endocrine tumors (fourth edition), the current American Joint Committee on Cancer (AJCC) staging system (eighth edition), the College of American Pathologists (CAP) protocol, and the International Collaboration on Cancer Reporting (ICCR) dataset. The aim is to provide a comprehensive review focused on the definitions and prognostic impacts of these crucial pathologic parameters. © 2019 by the authors. Licensee MDPI, Basel, Switzerland.
Keywords: extrathyroidal extension; lymphovascular invasion; ajcc staging; capsular invasion
Journal Title: Cancers
Volume: 11
Issue: 8
ISSN: 2072-6694
Publisher: MDPI  
Date Published: 2019-08-01
Start Page: 1100
Language: English
DOI: 10.3390/cancers11081100
PROVIDER: scopus
PUBMED: 31382401
PMCID: PMC6721517
DOI/URL:
Notes: Review -- Source: Scopus
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  1. Ronald A Ghossein
    482 Ghossein
  2. Bin   Xu
    227 Xu