Crucial parameters in thyroid carcinoma reporting - Challenges, controversies and clinical implications Journal Article
| Authors: | Xu, B.; Ghossein, R. A. |
| Article Title: | Crucial parameters in thyroid carcinoma reporting - Challenges, controversies and clinical implications |
| Abstract: | In the modern era, a pathology report of thyroid carcinoma requires the inclusion of numerous prognostically relevant histopathological features, e.g. the presence and extent of vascular and capsular invasion, extrathyroidal extension, the surgical margin status and the characteristics of nodal metastasis. These pathological features are crucial components of the initial risk stratification to determine the need for completion thyroidectomy and/or postoperative radioactive iodine ablation therapy. The current review aims to summarise the diagnostic criteria, the controversies, the prognostic impacts and the challenges of these pathological characteristics, focusing specifically on the parameters that are incorporated into the American Joint Committee on Cancer (AJCC) staging system, the College of American Pathologists (CAP) reporting template, the American Thyroid Association (ATA) and the National Comprehensive Cancer Network (NCCN) guidelines. © 2017 John Wiley & Sons Ltd |
| Keywords: | clinical feature; histopathology; review; postoperative care; recurrence risk; lymph node metastasis; practice guideline; risk assessment; radioactive iodine; thyroidectomy; clinical decision making; thyroid papillary carcinoma; disease specific survival; ablation therapy; predictive value; extrathyroidal extension; recurrence free survival; surgical margin; lymphovascular invasion; tumor invasion; ajcc staging; cancer prognosis; lymph vessel metastasis; human; priority journal |
| Journal Title: | Histopathology |
| Volume: | 72 |
| Issue: | 1 |
| ISSN: | 0309-0167 |
| Publisher: | Wiley Blackwell |
| Date Published: | 2018-01-01 |
| Start Page: | 32 |
| End Page: | 39 |
| Language: | English |
| DOI: | 10.1111/his.13335 |
| PROVIDER: | scopus |
| PMCID: | PMC5730489 |
| PUBMED: | 28782127 |
| DOI/URL: | |
| Notes: | Review -- Export Date: 2 January 2018 -- Source: Scopus |
